In a short-term study, more patients using SPRAVATO® plus oral antidepressant demonstrated rapid and superior reduction in depressive symptoms at four weeks compared to those who received placebo plus an oral antidepressant*
• Most of the reduction in depressive symptoms was seen at
24 hours
• Between 24 hours and four weeks, both groups continued to
improve; the difference in improvement between the groups
remained but did not appear to increase through four weeks